Restricted diffusion preceding gadolinium enhancement in large or tumefactive demyelinating lesions
نویسندگان
چکیده
منابع مشابه
Dominant perivenular enhancement of tumefactive demyelinating lesions in multiple sclerosis.
A 51-year-old woman presented with aphasia and bifrontal MRI lesions with punctuate and vague linear enhancement (figure). She improved spontaneously but 4 months later deteriorated due to the large mass and required cranial decompression. Innumerable, perivenular enhancements perpendicular to the lateral ventricles were seen within extensive bihemispheric white matter lesions. Multiple scleros...
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BACKGROUND AND PURPOSE Tumefactive demyelinating lesions (TDLs) can simulate intracranial neoplasms in clinical presentation and MR imaging appearance, and surgical biopsy is often performed in suspected tumors. Proton MR spectroscopy has been applied in assessing various intracranial diseases and is increasingly used in diagnosis and clinical management. Our purpose was to determine if multivo...
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BACKGROUND AND OBJECTIVES It is widely accepted that typical acute demyelinating lesions in relapsing-remitting multiple sclerosis (RRMS) exhibit vasogenic edema with increased diffusion, as demonstrated by an increased apparent diffusion coefficient on MRI. In contrast, acute ischemic lesions demonstrate cytotoxic edema with restricted diffusion. Recent reports have documented selected cases o...
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Whether or not recurrent tumefactive demyelinating lesions are a unique form of CNS demyelinating disease or part of the continuum of multiple sclerosis is a question raised by the case report on which this commentary is based. Detailed review and immunopathologic study of biopsy material may not only confirm or refute a diagnosis of demyelinating disease, but potentially uncover unique feature...
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Background and Purpose: It is important to differentiate between tumefactive demyelinating lesions (TDLs) and high grade gliomas to avoid unnecessary surgical procedures. However, this can be difficult on conventional MR imaging alone. Although MR perfusion weighted imaging has been reported to improve the accuracy of the diagnosis, this technique is limited in clinical practice since some pati...
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ژورنال
عنوان ژورنال: Neurology: Clinical Practice
سال: 2013
ISSN: 2163-0402,2163-0933
DOI: 10.1212/cpj.0b013e318283ff8e